| 专利名称： | POLYMER-CERAMIC-HYDROGEL COMPOSITE SCAFFOLD FOR OSTEOCHONDRAL REPAIR |
| 公开（告）号： | |
| 公开（公告）日： | 2007-01-24 00:00:00 |
| 申请（专利）号： | EP20050724534(EP1744794) |
| 申请日： | 2005-03-04 00:00:00 |
| 发明（设计）人： | UNIV COLUMBIA (US) |
| (申请)专利权（人）： | LU HELEN H (US);JIANG JIE (US) |
| 内容： | This invention pertains to materials and methods relating to the biological fixation of one tissue type to another different tissue type, i.e., the fixation of cartilage to bone. A scaffold apparatus for osteochondral tissue engineering is described. The apparatus comprises regions of varying matrices which provide a functional interface between multiple tissue types. Further, a method for preparing the scaffold apparatus is provided. Methods for treating osteochondral tissue injury and cartilage degeneration using the scaffold apparatus are also described. In addition, a method for evaluating cellmediated and scaffold-related parameters of development and maintenance of multiple tissue zones in vitro is described. |
发布日期：2007-08-21 15:11:00